Clinical Trials

Stylized computer image of lungs in blue shades

A clinical trial is a health-related research study in human beings that follows a pre-defined protocol. Interventional studies aim to answer specific questions about new therapies or new ways of using known treatments, while observational studies are those in which patients are observed and their outcomes measured by the investigators. Carefully conducted clinical trials are the responsible and most efficient way to identify treatments that are effective and safe.

There are several benefits to participating in a clinical trial. Participants have the opportunity to have an active role in their own health care, gain access to new investigational treatments before they are made widely available, and help others by contributing to the advancement of medical science through research.


  • Principal Investigator:

    Monica P. Goldklang, MD
    We are asking you to participate in a research study to determine if we can detect changes in enzymes in the blood that may influence lung function decline in COPD (chronic obstructive pulmonary disease), in particular after COPD exacerbations. The procedures of the study include a pulmonary function test (breathing test), a short questionnaire, and blood and urine samples. The duration of the study is two years: first visit, followed by a second visit two years later. If you were to experience a COPD exacerbation (increased cough, sputum, shortness of breath requiring oral or IV steroids and...
  • Principal Investigator:

    Jeanine Marie Theresa D'Armiento, MD
    Lymphangioleiomyomatosis (LAM) is a rare lung disease primarily affecting young women. Currently, LAM is often diagnosed in patients with radiology imaging (CTs) and/or lung biopsies; however, these methods can be imprecise, invasive, and/or can carry significant risks. The current study aims to devise a less invasive tool for diagnosis of this rare pulmonary disease. We are asking you to participate in a research study to determine whether different levels of a protein called HMGA2 among groups of people who have LAM and those who do not have LAM correlate with the occurrence and severity of...