Richard J. Levy, MD

Pediatric Anesthesiology, Pediatrics, Anesthesiology, Pediatric Critical Care Medicine
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Dr. Richard J. Levy, MD, FAAP is Professor of Anesthesiology and Pediatrics and Vice Chair for Pediatric Laboratory Research in the Department of Anesthesiology at Columbia University Medical Center. He is board certified in Anesthesiology, Pediatric Anesthesiology, Pediatrics, and Pediatric Critical Care Medicine. Dr. Levy completed his Pediatrics Residency at The Children’s Hospital of Philadelphia (CHOP) and his Anesthesiology Residency at the University of Pennsylvania. Subsequently, he completed fellowships in Pediatric Anesthesia/Cardiac Anesthesia and Pediatric Critical Care Medicine at CHOP. As a trainee on an NIH-Institutional Training Grant (T32) and subsequent PI on an NIH-mentored clinical scientist development award (K08), his initial area of investigation focused on acquired mitochondrial dysfunction in the murine septic heart and his lab identified several novel therapeutic interventions targeting sepsis-induced myocardial depression, resulting in two patent applications. Over the last few years, he has focused his investigation on the effect of different environmental exposures on the developing brain. He has published over 75 original manuscripts, is an associate editor for Survey of Anesthesiology, and regular reviewer for Critical Care Medicine, Anesthesia & Analgesia, the World Journal for Pediatric and Congenital Heart Surgery, and the American Journal of Physiology. Dr. Levy has also served as an ad hoc reviewer for Science, Nature Medicine, Nature Reviews Cardiology, and PLOS One. In addition, he is a member of the Society of Pediatric Anesthesiology Grant Review Committee and is a grant reviewer for the FAER Medical Student Year Long Fellowship program.

Areas of Expertise / Conditions Treated

  • Anesthesia
  • Pediatric Cardiac Anesthesia

Academic Appointments

  • Professor of Anesthesiology and Pediatrics

Administrative Titles

  • Vice Chair for Pediatric Laboratory Research

Hospital Affiliations

  • NewYork-Presbyterian Morgan Stanley Children's Hospital
  • NewYork-Presbyterian / Columbia University Irving Medical Center


  • Male

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Insurance Accepted


  • EPO
  • Great West (National)
  • HMO
  • POS
  • PPO


  • Medicare Managed Care
  • PPO


  • ConnectiCare
  • EPO
  • Essential Plan
  • HMO
  • Medicaid Managed Care
  • Medicare Managed Care
  • POS
  • PPO
  • Select Care (Exchange)
  • Vytra

Local 1199

  • Local 1199

MagnaCare (National)

  • MagnaCare


  • Railroad
  • Traditional Medicare


  • Special Needs


  • Compass (Exchange)
  • Empire Plan
  • HMO
  • Medicare Managed Care
  • POS
  • PPO

*Please contact the provider’s office directly to verify that your particular insurance is accepted.

Credentials & Experience

Education & Training

  • MD, 1995 New York Medical College
  • Residency: Hospital of the University of Pennsylvania
  • Residency: Children's Hospital of Philadelphia
  • Fellowship: Children's Hospital of Philadelphia

Committees, Societies, Councils

1998-present American Society of Anesthesiologists

2001-present Society of Critical Care Medicine

2006-2008 Research Committee Member, SCCM

2005-present Society of Pediatric Anesthesia (SPA)

2006-present Congenital Cardiac Anesthesia Society

2008-present International Anesthesia Research Society

2013-present Research Committee Member, SPA

2013-present NIH NHLBI/Pediatric Heart Network Data Monitoring Safety Board, Ad Hoc member

2013-present American Academy of Pediatrics

2015-present SPA Grants Review Committee

2015-present Society for Neuroscience

Board Certifications

  • Pediatric Anesthesiology
  • Pediatrics
  • Anesthesiology
  • Pediatric Critical Care Medicine

Honors & Awards

1992-1995 New York Medical College Trustees' Scholarship

1994-1995 Alpha Omega Alpha Medical Honor Society

2001 Young Investigator Award, American Society of Critical Care Anesthesiologists

2010 John C. Downes Research Award, American Academy of Pediatrics

2010 Best of Meeting Award, International Anesthesia Research Society

2011 Association of University Anesthesiologists

2013 Fellow of the American Academy of Pediatrics

2017 Kosaka Best of Meeting Abstract Award Finalist, International Anesthesia Research Society


Our lab is interested in evaluating the neurotoxic and neuroprotective effects of low dose carbon monoxide (CO) in the developing brain. We are specifically focused on CO-mediated neuroprotection in the context of an anesthetic exposure. The phenomenon of re-breathing one’s own exhaled CO is unique to the semi-closed anesthesia breathing circuit. In early work, we found that exposure to low concentration CO alone inhibited natural programmed cell death in the developing murine brain and prevented necessary elimination of excess and aberrant neurons. This resulted in impaired social behavior and memory and learning later in life. In subsequent work, we found that the anti-apoptotic effects of CO were able to offset and prevent the deleterious effects of anesthetic agents in the developing brain. As a result, we are currently evaluating the mechanisms of anesthesia-induced overactivation of cytochrome oxidase within forebrain mitochondria in immature rodents and determining how CO modulates cytochrome oxidase activity during anesthetic exposure to provide neuroprotection. The ultimate goal of our work is to develop low dose CO as a novel therapeutic agent to prevent anesthesia-induced neurotoxicity.

In other work, we are studying fragile X syndrome, the leading known inherited intellectual disability and the most common genetic cause of autism. We are utilizing Fmr1 KO mice as a model of fragile X syndrome, intellectual disability, and autistic behavior. In preliminary work, we found a defect in the mitochondrial pathway of apoptosis in the forebrain of newborn male Fmr1 mutant mice. This led us to explore oxidative phosphorylation and bioenergetic capacity in these mice. We are currently studying mitochondrial function in the developing brain of Fmr1 KOs and determining the genetic predisposition to oxidative stress and neurodegeneration. We aim to use this model to identify neurotoxic and neurosparing anesthetic agents for FXS and related diseases. The ultimate goal of this work is to develop safe and precise anesthetic approaches for children with FXS.